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Myriad RBM
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SomaLogic
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Siemens AG
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The Human N Terminal Pro BNP Antibody from R D Systems is a mouse monoclonal antibody to BNP This antibody reacts with human The Human N Terminal Pro BNP Antibody has been validated for the
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pro-Brain Natriuretic Peptide, C-Terminal (proBNP) (a.a. 77-108)
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Image Search Results
Journal: Proteomics
Article Title: Comparison of Proteomic Assessment Methods in Multiple Cohort Studies
doi: 10.1002/pmic.201900278
Figure Lengend Snippet: Correlation coefficients for the 63 proteins assessed between the SOMAscan and Myriad RBM platform in both COPDGene and SPIROMICS. Presence or absence of a cis pQTL variant (p <1 × 10 −4 within 1 megabase of the gene encoding the protein product) is also listed. r s , estimated Spearman’s rho. We have separated out low correlation (r s <0.3 in both cohorts) and high correlation (r s ≥0.7 in both cohorts) proteins, with all other proteins listed in the moderate correlation category. We also list whether aptamers have cis pQTLs found in genetic analyses from either of the larger AGES [ 7 ] and INTERVAL [ 25 ] studies using SOMAscan data or from previous analysis of the full published sample size in SPIROMICS and COPDGene cohorts with Myriad RBM data [ 16 ] . Finally, we list if an aptamer has been validated as having at least some binding to its target by mass spectrometry in AGES [ 7 ] , and whether an aptamer has comparable binding in cross-reactivity testing against homologous proteins (at least 40% sequence homology) in [ 25 ] . UniProt ID, gene name, and aptamer SomaId are listed in Supplementary Table 2 .
Article Snippet: A few proteins had low missingness in only one study, three in COPDGene (SL000248/Alpha-1-antichymotrypsin, r s =0.33, n= 370, SL001802/IFN-g, r s =0.11, n= 339, SL002621/midkine, r s =0.23, n= 369) and one in
Techniques: Variant Assay, Binding Assay, Mass Spectrometry, Sequencing, Coagulation, Glycoproteomics